NASA Jet Propulsion Laboratory California Institute of Technology JPL Home Earth Solar System Stars & Galaxies Science & Technology Bring the Universe to You JPL Email News RSS Podcast Video
Follow this link to skip to the main content

Home
Research
Opportunities
Community
News and Events
Announcements
News Board
Seminars
ST icon
Office of the Chief Scientist and Chief Technologist
News and Events

Seminars

Average Rating: 0 / 5 (0 ratings)
  •   star rating help
    How Do I Rate This?
    The blue stars show the average user rating for this item. To add your own rating, move your cursor over the stars to highlight them in gold, and click to show your rating. One star highlighted is the lowest rating, all five is the highest. Once you have rated an item, your rating is added to the average.
Single-Protein Nanomechanical Mass Spectrometry
Single-Protein Nanomechanical Mass Spectrometry

Date: Monday, March 4, 2013
Time: 4:00pm
Location: Steele, Caltech
Speaker: Mehmet Hanay

KNI / MDL Joint Seminar Series


Nanoelectromechanical systems (NEMS) resonators can detect inertial mass with exceptional sensitivity. Previously, mass spectra from several hundred adsorption events were assembled in NEMS-based mass spectrometry using statistical analysis. Here, we report the first realization of single-molecule NEMS-based mass spectrometry in real time. As each molecule in the sample adsorbs upon the NEMS resonator, its mass is determined by continuously tracking two driven vibrational modes of the device. We demonstrate the potential of NEMS-based mass spectrometry by analyzing IgM antibody complexes. NEMS-MS is a unique and promising new form of mass spectrometry: it can resolve neutral species, provides resolving power that increases markedly for very large masses, and allows acquisition of spectra, molecule-by-molecule, in real time.

Light refreshments will be served after the seminar.

Site Manager:  Brian Knosp
Webmasters:  Cornell Lewis, Maryia Davis

JPL Clearance:  CL#08-4147